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Pathophysiology of herpes simplex

Herpes simplex pathophysiology - wikido

HSV-1 can cause genital herpes, but it more commonly causes infections of the mouth and lips, so-called fever blisters. HSV-1 infection of the genitals can be caused by oral-genital or genital-genital contact with a person who has HSV-1 infection. Genital HSV-1 outbreaks recur less regularly than genital HSV-2 outbreaks Herpes simplex viruses spread from person to person through close contact. You can get a herpes simplex virus from touching a herpes sore. Most people, however, get herpes simplex from an infected person who does not have sores. Doctors call this asymptomatic viral shedding HSV is a DNA virus that commonly affects humans. Infection occurs by direct contact of skin or mucous membrane with virus-laden lesions or secretions. HSV type 1 (HSV-1) is primarily responsible.. Pathophysiology and Epidemiology of Herpes Simplex Virus Infection Kenneth H. Fife, MD, PHD: Herpes infections are a little difficult to get a handle on, in part because they are not reportable, so all of our data on the incidence and prevalence of HSV disease is based on some kind of indirect measurement and extrapolation to other populations Infection with herpes simplex virus, commonly known as herpes, can be due to either herpes simplex virus type 1 (HSV-1) or herpes simplex virus type 2 (HSV-2). HSV-1 is mainly transmitted by oral-to-oral contact to cause infection in or around the mouth (oral herpes)

Herpes simplex: Who gets and cause

  1. Herpes simplex viruses are ubiquitous, host-adapted pathogens that cause a wide variety of disease states. Two types exist: herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2). Both are closely..
  2. Genital herpes is a common sexually transmitted infection caused by the herpes simplex virus (HSV). Sexual contact is the primary way that the virus spreads. After the initial infection, the virus lies dormant in your body and can reactivate several times a year. Genital herpes can cause pain, itching and sores in your genital area
  3. The herpes simplex virus, also known as HSV, is an infection that causes herpes. Herpes can appear in various parts of the body, most commonly on the genitals or mouth. There are two types of the..

Herpes simplex virus infections in the immunocompromised host are clinically more severe, may be progressive, and require more time for healing. Manifestations of herpes simplex virus infections in this patient population include pneumonitis, esophagitis, hepatitis, colitis, and disseminated cutaneous disease Pathophysiology Herpes is contracted through direct contact with an active lesion or body fluid of an infected person. Herpes transmission occurs between discordant partners; a person with a history of infection (HSV seropositive) can pass the virus to an HSV seronegative person Sometimes the herpes simplex virus can spread to one or both eyes. If this happens, you can have pain, light sensitivity, discharge, and a gritty feeling in the eye. Without prompt treatment, scarring of the eye may result. Scarring can lead to cloudy vision and even loss of vision

Herpes simplex virus (HSV) is a human herpesvirus that causes HSV encephalitis (HSE), which is the commonest fatal sporadic encephalitis in humans. 1, 2 About 90% of all HSE cases in adults and children are due to HSV-1, while HSV-2 is associated with HSE in neonates, in which there is a disseminated infection, and in immunocompromised patients, such as those with renal transplants or HIV. Herpes simplex viruses (human herpesviruses types 1 and 2) commonly cause recurrent infection affecting the skin, mouth, lips, eyes, and genitals. Common severe infections include encephalitis, meningitis, neonatal herpes, and, in immunocompromised patients, disseminated infection. Mucocutaneous infections cause clusters of small painful. Genital herpes is an STD caused by two types of viruses. The viruses are called herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2). What is oral herpes? Oral herpes is usually caused by HSV-1 and can result in cold sores or fever blisters on or around the mouth

Pathophysiology Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are acquired at mucosal surfaces or at breaks in the skin. The virus initially replicates in the epidermis, then infects sensory or autonomic nerve endings and travels by retrograde axonal transport to sensory ganglia HSV (Herpes Simplex Virus) keratitis is an infection of the cornea—the clear dome that covers the colored part of the eye—that is caused by HSV. The infection usually heals without damaging the eye, but more severe infections can lead to scarring of the cornea or blindness. HSV keratitis is a major cause of blindness worldwide 1 Herein, we review the pathophysiology, differential diagnosis, and clinical and radiological features of herpes simplex virus-1 encephalitis in adults, including a discussion of the most common complications and their treatment. While great progress has been made in the treatment of this life-threatening infection, a majority of patients will. Herpes simplex viruses -- more commonly known as herpes -- are categorized into two types: herpes type 1 (HSV-1, or oral herpes) and herpes type 2 (HSV-2, or genital herpes). Most commonly, herpes..

Pathophysiology and Epidemiology of Herpes Simplex Virus

HSE is a type of infectious encephalitis which happens when herpes simplex virus (HSV) enters the brain. HSV can be of two types: HSV1 and HSV2. HSV1 is mainly associated with infections of mouth and throat early in life often without symptoms, but lately, it has also been associated with genital herpes Genital herpes is a common sexually transmitted disease, affecting more than 400 million persons worldwide. It is caused by herpes simplex virus (HSV) and characterized by lifelong infection and. Herpes simplex recurrence has long been associated with stress, fever and sunburn. This study sheds light on how all these triggers can lead to herpes simplex-associated disease Causes. Cold sores are caused by certain strains of the herpes simplex virus (HSV). HSV-1 usually causes cold sores.HSV-2 is usually responsible for genital herpes.But either type can spread to the face or genitals through close contact, such as kissing or oral sex

Herpes simplex virus - World Health Organizatio

  1. Herpes simplex type 1 typically causes cold sores or blisters around the mouth but can be transmitted to the genital area by way of oral sex (oral to genital contact). HSV-2 (genital herpes) are commonly spread through sexual activity, such as anal, vaginal and oral sex. HSV-1 (oral herpes) can be spread through oral bodily fluids contacts like.
  2. Herpes simplex encephalitis (HSE) is an acute or subacute illness that causes both general and focal signs of cerebral dysfunction
  3. Oral herpes — also known as cold sores or fever blisters — is a common viral infection of the mouth. Of all the adults in the U.S., it's estimated that 50% to 80% have oral herpes.Roughly 90% of adults in the U.S. are exposed to herpes simplex 1, the virus that causes oral herpes, by the time they are 50 years old
  4. Herpes Simplex Infection with herpes simplex virus (HSV) is one of the most common infections in the world. There are two types of HSV—herpes simplex virus 1 and herpes simplex virus 2—that cause..
  5. About 90% of cases of herpes encephalitis are caused by herpes simplex virus-1 (HSV-1), the same virus that causes cold sores. 57% of American adults are infected with HSV-1, which is spread through droplets, casual contact and sometimes sexual contact, though most infected people never have cold sores
  6. Herpes simplex is commonly referred to as cold sores or fever blisters, as recurrences are often triggered by a febrile illness, such as a cold. What causes herpes simplex? Herpes simplex is caused by one of two types of herpes simplex virus (HSV), members of the Herpesvirales family of double-stranded DNA viruses
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Overview Pathophysiology: Contact between a person with HSV and one without antibodies occurs to cause the infection. The host will suppress the virus as an immune response. The virus will travel fro site of infection on skin or mucosa to the dorsal root ganglion and then latency will occur. Once in latency, it can reactivate [ Herpes infections are very common. Fifty to 80 percent of American adults have oral herpes (HSV-1), which causes cold sores or fever blisters in or around the mouth. Genital herpes, caused by HSV-1 or HSV-2, affects one out of every six people in the U.S. age 14 to 49. Genital herpes infections can. Causes of encephalitis include herpes simplex virus, varicella zoster virus, arboviruses, and enteroviruses. Encephalitis may also occur secondary to other disorders. Meningitis is a disorder characterized by inflammation of the membranes surrounding the brain and spinal cord. There are many types of meningitis, caused by many different.

Herpes Simplex: Background, Microbiology, Pathophysiolog

  1. The herpes simplex virus (HSV) is a common virus that causes episodes of small, fluid-filled blisters on the mouth, lips, skin, eyes, and/or genitals. This very contagious infection is spread.
  2. Whether you call it a cold sore or a fever blister, oral herpes is a common infection of the mouth area that is caused by herpes simplex virus type 1 (HSV-1). Fifty percent to 80 percent of U.S. adults have oral herpes. According to the National Institutes of Health, about 90 percent of adults have been exposed to the virus by age 50
  3. Herpes is a mild condition that causes small sores to appear on the skin. People develop herpes after being exposed to the herpes simplex virus (HSV).There are two types of this virus
  4. Herpes simplex virus type 2 (HSV-2). This type is most often linked to genital herpes infections. Both types of HSV can infect both the mouth and the genitals. Once infected, a person will have the herpes simplex virus for the rest of their life. When the virus is not active, it is dormant in a group of nerve cells
  5. Herpes simplex type 1 typically causes cold sores or blisters around the mouth but can be transmitted to the genital area by way of oral sex (oral to genital contact). HSV-2 (genital herpes) are commonly spread through sexual activity, such as anal, vaginal and oral sex. HSV-1 (oral herpes) can be spread through oral bodily fluids contacts like.
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  7. Herpes simplex, infection of either the skin or the genitalia caused by either of two strains of herpes simplex virus. Herpes simplex virus type 1 (HSV-1) is transmitted orally and is responsible for cold sores and fever blisters, typically occurring around the mouth, whereas herpes simplex virus type 2 (HSV-2) is transmitted sexually and is.
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Genital herpes - Symptoms and causes - Mayo Clini

The finding could lead to new ways to prevent recurring cold sores and herpes-related eye disease, U.S. and British researchers say. More than half of Americans are infected with herpes simplex virus Herpes Simplex Virus consists of two types; HSV-1 and HSV-2. HSV-1 occurs around the mouth, and is usually in the form of cold sores. On the other hand, HSV-2 occurs most often near the genitals, and it is also called genital herpes. HSV-1 spreads through oral contact by the sharing of toothbrushes and other accessories Are Cold Sores and Herpes the Same Thing? No. Herpes can cause cold sores, but they are not the same thing. What Causes Cold Sores? Cold sores are caused by the herpes virus, usually herpes simplex type 1 virus (HSV-1). The herpes simplex type 2 virus (HSV-2) typically causes genital herpes

Herpes Simplex: Causes, Symptoms, Diagnosis, and Mor

  1. Once a person contracts the herpes simplex virus (HSV-1), it usually causes an initial outbreak of cold sores.. Then, the virus remains in the person's body for the rest of their life, causing.
  2. Herpes simplex type 1: In the eye, it usually causes an infection of the cornea. This infection is called herpes simplex keratitis. This infection is called herpes simplex keratitis. Although both of these problems are caused by a herpes virus, different medications are sometimes needed to treat the appearances of the disease
  3. the pathophysiology, differential diagnosis, and clinical and radiological features of herpes simplex virus-1 encephalitis in adults, including a discussion of the most common complications and their treatment. While great progress has been made in the treatment of this life-threatenin
  4. Herpes simplex virus is a highly contagious human pathogen that has widespread infections in the oro-facial region which is associated with HSV-1. This single review article can provide the entire knowledge about the pathogenesis, its interesting property of latency and clinical features of HSV infection under one tree

Herpes simplex virus type 2 (HSV-2) infection is responsible for significant neurological morbidity, perhaps more than any other virus. Seroprevalence studies suggest that as many as 45 million people in the United States have been infected with HSV-2, and the estimated incidence of new infection is 1 million annually Herpes simplex virus type 2 (HSV-2) continues to be a common infection, affecting approximately 22% of adults ages 12 and older, representing 45 million adults in the United States alone. [4] While HSV-1 often affects the perioral region and can be known to cause genital lesions, HSV-2 is more commonly the consideration when patients present. Q: How common is neonatal herpes simplex? A: About 1 out of every 3,500 babies born in the United States contracts neonatal herpes simplex. Q: Why is neonatal herpes simplexa problem? A: Neonatal herpes simplex is a serious condition that requires immediate treatment. If left untreated, the virus can cause brain and spinal cord function, as. Oral herpes is a viral infection mainly of the mouth area and lips caused by a specific type of the herpes simplex virus. Oral herpes is also termed HSV-1, type 1 herpes simplex virus, or herpes labialis. The virus causes painful sores on the upper and lower lips, gums, tongue, roof of the mouth, inside the cheeks or nose, and sometimes on the face, chin, and neck Herpesviral encephalitis, or herpes simplex encephalitis (HSE), is encephalitis due to herpes simplex virus.It is estimated to affect at least 1 in 500,000 individuals per year, and some studies suggest an incidence rate of 5.9 cases per 100,000 live births. About 90% of cases of herpes encephalitis are caused by herpes simplex virus-1 (HSV-1), the same virus that causes cold sores. 57% of.

Herpesviruses - Medical Microbiology - NCBI Bookshel

Herpes simplex - Wikipedi

Herpes simplex virus type 1 (HSV-1) more commonly causes herpes labialis; however, it is also an increasing cause of initial episodes of genital herpes. HSV-1 is also associated with HSV encephalitis. HSV type 2 (HSV-2) causes genital herpes. HSV-1 and HSV-2 are members of the Herpesviridae family and are related to varicella-zoster virus. Herpes simplex (HSV-1 or HSV-2), the viruses that can cause cold sores or genital herpes, respectively, are not the same virus as herpes zoster, though they all come from the same large family of viruses. Both HSV-1 and HSV-2 are spread through skin-to-skin contact, and they are slightly different strains from the same viral family Herpes can't be cured, but outbreaks can be managed and prevented. When the topic of herpes arises, you might remember terrible slideshows of sexually transmitted diseases from health class. But herpes doesn't have to be scary or shameful. The herpes simplex virus is very common, and it's possible to carry it without having any symptoms Herpes simplex encephalitis is a rare neurological condition that is characterized by inflammation of the brain (encephalitis). People affected by this condition may experience a headache and fever for up to 5 days, followed by personality and behavioral changes; seizures; hallucinations; and altered levels of consciousness.Without early diagnosis and treatment, severe brain damage or even.

Erythema multiforme usually occurs in adults 20 to 40 years of age,6 although it can occur in patients of all ages.1 Herpes simplex virus (HSV) is the most commonly identified etiology of this. Once you have a herpes simplex infection, cold sores often form because of stress or illness. Some may form without an identifiable trigger. Risk Factors for Becoming Infected With Herpes Simplex 1 Virus Exposure to Someone With Cold Sores. Herpes simplex virus type 1 (HSV-1) can be spread by close contact with someone who has a cold sore Herpes simplex virus type 1 (HSV-1) more commonly causes herpes labialis; however, it is also an increasing cause of initial episodes of genital herpes. Ryder N, Jin F, McNulty AM, et al. Increasing role of herpes simplex virus type 1 in first-episode anogenital herpes in heterosexual women and younger men who have sex with men, 1992-2006 Neonatal herpes simplex virus (HSV) infection is among the most severe perinatal infections. Most (85%) neonatal HSV infections are acquired during delivery, although in utero (5%) and postnatal (10%) infections do occur ().The risk for transmission to the newborn is much higher in women with primary HSV infections ().Neonatal herpes can be localized to skin, eyes, and mouth (≈45% of cases. Herpes eye disease can also affect the white part of your eye (sclera) or the colored part of your eye (iris). It is a major cause of blindness worldwide. Herpes simplex virus is common. It generally infects a majority of adults and a slightly smaller percentage of children. Many people infected with the virus have no symptoms

Causes of Herpes Labialis. Herpes labialis is caused by herpes simplex virus. The family of herpes simplex viruses contains various strains but only eight are now known to affect or infect humans. These have been given numbers one through eight. The most common cause of herpes labialis is herpes simplex virus type one Herpes simplex 2 causes genital herpes and there will be obvious symptoms. It may also spread beyond the genital area and there may be symptoms not usually associated with genital herpes. Orofacial herpes symptoms may also appear if the virus spreads well beyond the genital area. Oral sex is almost always the cause of such a spreading of the virus Herpes esophagitis is an inflammation of the esophagus caused by infection with a herpes simplex virus (HSV). The esophagus is part of the throat, the tube that connects the mouth to the stomach. There are many possible causes of esophagitis. Herpes esophagitis is caused by HSV-1 or HSV-2, although it rarely occurs in individuals who have a. Pathophysiology. Herpes simplex is a viral disease caused by both herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2). The infection is common in the United States and abroad and is usually categorized based on the site of infection, although both HSV-1 and HSV-2 can cause infections anywhere on the body Herpes simplex eye infections are a potentially serious type of eye infection. They're caused by a virus called herpes simplex - usually the herpes simplex virus type 1 (HSV-1), which also causes cold sores.. It's important to get medical help if you think you may have the infection, as your vision could be at risk if it's not treated

Causes Of Herpes Simplex Virus Infection. As aforementioned, the herpes virus is contagious and can easily pass on from one person to another through skin-to-skin contact or direct contact with the mucous membranes such as the mouth, eyes, genitals and anus, where the virus is in high infectious form HSV (Herpes Simplex Virus) WHat causes genital herpes. HSV-1 causes cold sores HSV-2 affects genitals. What is the difference between HSV-1 and HSV-2? itching, sores, pain, blisters, bleeding, tender, fever, headache, swollen, nymph moles Alerts and Notices Synopsis Herpes simplex pneumonia (HSP), or tracheobronchial infection, occurs when the respiratory tract is infected with the herpes simplex virus (HSV). HSP typically occurs in immunosuppressed patients such as those who are neutropenic from chemotherapy, immunosuppressed following organ transplantation, or are immunocompromised from HIV/AIDS or other immunodeficiency. Learn how the herpes simplex virus infects cells to survive and cause symptoms

Herpes Simplex Keratitis - Europe - American Academy of

Herpes simplex: Signs and symptom

Herpes simplex encephalitis Journal of Neurology

Herpes Simplex Virus (HSV) Infections - Infectious

Herpes Simplex Virus (HSV) Stromal Keratitis and Endotheliitis Pathophysiology. The pathophysiology of HSK is complex and remains incompletely understood. Current data suggests that CD4 T cells of the adaptive immune system are required for the development and maintenance of HSK Alerts and Notices Synopsis This topic discusses disseminated herpes simplex virus in adults and children. Neonatal herpes simplex virus is addressed separately. Infection with herpes simplex virus type 1 or herpes simplex virus type 2 (HSV-1 or HSV-2) usually presents as discrete groups of painful vesicles on orolabial or genital skin. However, in some instances, HSV infection may be diffuse. Epidemiology. Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) can cause disease at any age. It is generally regarded that HSV-1 is transmitted primarily through contact with infected oral secretions and that HSV-2 is acquired primarily through contact with infected genital secretions For instance, oral herpes will involve the mouth or face. It might lead to groups of small blisters frequently known as fever blister or cold sores, or might only lead to a sore throat. Symptoms of Herpes Simplex Virus. Genital herpes might show minimal signs or form small blisters which break open and lead to small ulcers

Herpes simplex virus (HSV) is a very common, lifelong infection that often is asymptomatic. In the 2015-2016 National Health and Nutrition Examination Survey, the prevalence of HSV type 1 (HSV-1) was 47.8% and HSV type 2 (HSV-2) was 11.9%. Globally, the incidence of HSV keratitis is 1.5 million yearly, including 40,000 new cases that result in. Yes, cold sores are herpes. While commonly referred to as cold sores, the blisters appearing around a person's mouth are a form of the herpes simplex virus (HSV). There are two main strains of herpes: HSV-1 is most often responsible for cold sores around the mouth. In 2016, 3.7 billion people under the age of 50 worldwide had HSV-1 infections Herpes simplex virus (HSV) is a rarely reported cause of viral hepatitis. Aggressive in nature, most cases of HSV hepatitis rapidly progress to fulminant hepatic failure. Present day, its pathogenesis is yet to be elucidated, but its complications and associated high mortality rate are clear. Clinically, its symptoms mimic those of other causes of acute hepatic failure thus making the. The herpes simplex virus causes a variety of infections, characterized by dormant periods with no symptoms and sporadic outbreaks of red, itchy, painful blisters. Generally, there are two types of herpes: genital herpes and oral herpes (also called cold sores or fever blisters). However, herpes lesions from both types can be found anywhere on. Herpes simplex virus hides in nerve cells for life, so once you have herpes simplex you always have it, she said. Sometimes, it comes out of hiding, and this can cause clinical disease, like.

STD Facts - Genital Herpe

Medical Pictures Info – Periorbital Cellulitis

Herpes simplex virus infection - Etiology BMJ Best

Herpes simplex viruses also cause encephalitis, an infection of the brain. Children with encephalitis have fever, headache, irritability, and confusion. Seizures are common. Herpes simplex type 2 often causes a mild form of meningitis that does not cause long-term problems or brain damage Herpes viruses. Herpes viruses are the other common cause of viral meningitis in adolescents and adults in developed countries[2]. Herpes viruses include the herpes simplex viruses (HSVs) and varicella zoster virus - the same virus that causes chickenpox and shingles What causes oral herpes simplex virus infections? Oral HSV infections are easily spread through close, personal contact with someone who has HSV. The infection may be spread when you touch the blisters and then touch your eyes, mouth, nose, or a cut. The infection can also spread through a kiss or on a shared eating utensil

Herpetic stomatitis is an infection caused by the herpes simplex virus (HSV), or oral herpes. Young children commonly get it when they are first exposed to HSV. The first outbreak is usually the most severe. HSV can easily be spread from one child to another. If you or another adult in the family has a cold sore, it could have spread to your. Neonatal Herpes Simplex Virus (HSV) Infection. Neonatal herpes simplex virus infection is usually transmitted during delivery. A typical sign is vesicular eruption, which may be accompanied by or progress to disseminated disease. Diagnosis is by viral culture, polymerase chain reaction testing, immunofluorescence, or electron microscopy Oral herpes (herpes simplex labialis) is a very common disease that causes small, painful cold sores and fever blisters of the mouth, lips or gums. Oral herpes is most often caused by HSV-1, but HSV-2 may also be responsible in some cases. It is estimated that 50% to 80% of all American adults have oral herpes, according to the Centers for. t1 - herpes-simplex virus as cause of bell's palsy AU - McCormick, David P. N1 - Funding Information: F.l.M.L.T., for technical assistance; to the paediatricians of the Children's Hospital who allowed us to study patients under their care; and to the nursing staff for their helpful cooperation

Basics of HSV (Herpes Simplex Virus) Keratitis Contact

Punctate Keratitis

1. Transmission. Herpes simplex virus is typically infectious during the 5-10 days it takes to heal skin lesions as well as during asymptomatic shedding in saliva. 34 In 2005, Kaufman et al used a quantitative PCR technique to detect HSV-1 DNA in the tears and saliva of 50 asymptomatic HSV-infected patients It is caused by a virus called the varicella-zoster virus. It is the same virus that causes chickenpox. Anyone who has had chickenpox in the past may develop shingles. Shingles is sometimes called herpes zoster. (Note: this is very different to genital herpes which is caused by a different virus called herpes simplex. Why genital herpes comes back. Genital herpes is caused by a virus called herpes simplex. Once you have the virus, it stays in your body. It will not spread in your body to cause blisters elsewhere. It stays in a nearby nerve and causes blisters in the same area. If you can, avoid things that trigger your symptoms. Triggers can include

Keratitis, Interstitial – Medical BlogVaricella Zoster VirusPapilledema - Ophthalmology - Medbullets Step 2/3

Herpes Myth: Herpes isn't that common, and I am unlikely to get it. Fact about herpes: Herpes is very common and may be caused by both herpes simplex type 1 and herpes simplex type 2 (HSV-1 or HSV-2). HSV-1 causes cold sores on the mouth, and up to 80% of the population has this virus Causes & Symptoms of Eye Herpes. Keratitis, or inflammation or infection of the eyes, has several potential causes, including bacteria, parasites, overexposure to ultraviolet (UV) light, or a virus (specifically HSV-1 or HSV-2). There are roughly 20,000 new reported cases of eye herpes in the United States every year, with 48,000 total reported. Herpes simplex keratitis (HSK) is the leading cause of corneal blindness in developed countries. In UK, responsible for 1 in 10 corneal transplants. Predisposing factors. Poor general health, immunodeficiency, fatigue Systemic or topical steroids, or other immunosuppressive drug Herpetic keratitis is a rare complication of cataract surgery. We describe 3 cases of herpes simplex keratitis after cataract surgery in eyes with no clinical history of this disease. Methods: Three patients underwent uneventful phacoemulsification of cataract with intraocular lens implantation. All were treated postoperatively with topical.

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